Medical Marijuana: Application in Obesity,Arthritis,Infertility treatment and more
The US state of Colorado has allowed sale of cannabis for recreational use in 2014. It was legal in Amsterdam. The medical properties of marijuana have been documented in ancient Chinese and Indian Vedic texts. Bhaang prepared from bud of cannabis is a popular drink during festivals such as Holi in the Indian subcontinent.
With advanced research increasingly providing evidence of great medical benefits, the odds are turning in favour of a once outlawed drug as a potential medicine for alleviating pain, helping patients suffering from disorders as diverse as arthritis, obesity and motor neuron diseases.
The first endogenous cannabinoid, arachidonylethanolamide or Anandamide (a Sanskrit word meaning blissful amide) was isolated in Israel in 1992.
The research and discoveries of the cannabinoid receptors, endocannabinoids and the related enzymes of the endocannabinoid system have a role in most of the physiological systems. According to expert scientist Vincenzo Di Marzo the endocannabinoid system plays a regulatory role in terms of messages that mediate the pathways of eating, sleeping and relaxing.
The receptors for endocannabinoid exist in the adipose tissue, pancreas, liver, GI tract, skeletal muscles, heart and the reproduction system.
The role of endocannabinoids in mammalian reproduction is an emerging research area given their implication in fertilization, preimplantation embryo and spermatogenesis. The relevant preclinical data on endocannabinoid signalling open up new perspectives as a target to improve infertility and reproductive health in humans.
Endocannabinoid system: An overview of its potential in current medical practice. Mouslech Z, Valla V.